Drug intelligence / Profile preview

fish oil + curcumin

Development stage
Unknown
Lead developer
Nordic Naturals
Modality
Nucleic Acid-Directed Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Fish oil + curcumin is a combination dietary supplement containing two bioactive ingredients—fish oil (a source of omega-3 polyunsaturated fatty acids such as EPA and DHA) and curcumin (the principal active compound in turmeric). This combination is designed to leverage the anti-inflammatory, antioxidant, lipid-lowering, neuroprotective, and metabolic benefits attributed to both components. Fish oil acts primarily by providing long-chain omega-3 fatty acids that modulate inflammatory pathways and support cardiovascular health. Curcumin exerts pleiotropic effects including inhibition of NF-κB activation (a key regulator of inflammation), reduction of oxidative stress, modulation of lipid metabolism, improvement in insulin sensitivity, and potential neuroprotection. The combination has been studied for its effects on reducing systemic inflammation (e.g., lowering C-reactive protein), improving insulin resistance and blood lipids in individuals at risk for type 2 diabetes or cardiovascular disease[5][6], supporting joint health[10], promoting recovery from musculoskeletal symptoms[1], enhancing cognitive function[7], modulating colonic inflammation via suppression of NF-κB activity[2], and potentially reducing tumor growth in preclinical models. Commercially available products may include additional antioxidants or bioavailability enhancers.

Brand names
Ultimate Omega + CurcuminOmega-3 2100 with TurmericOmega3 2100 with TurmericOmega 3 2100 with Turmeric
Other names
fish oil and curcuminomega-3 fatty acids and curcuminomega3 fatty acids and curcuminomega 3 fatty acids and curcuminFO-cur
02

Targets

NF-κBPTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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