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FiteBac
- Development stage
- Unknown
- Lead developer
- FiteBac Technology
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Topical, Dental
01
Overview
FiteBac is a brand of antimicrobial products centered on a proprietary quaternary ammonium silane (QAS) technology, most notably the molecule **K21**. This technology provides persistent antimicrobial protection by electrostatically attracting and mechanically disrupting microbial cell membranes, rather than relying on leaching chemicals. In skin care, FiteBac is formulated as a gel containing a germicide (often benzalkonium chloride) and a silicone polymer that creates a durable, breathable barrier on the skin, making it effective for hand sanitization and the management of **hand dermatitis** (eczema). In dentistry, FiteBac K21 is utilized as a cavity cleanser and root canal irrigant, where it penetrates bacterial biofilms (such as *E. faecalis*) and promotes wound healing without compromising the bond strength of dental restorations like resin-modified glass ionomer cements.
- Brand names
- FiteBacFiteBac Skin Care GelFiteBac Dental
- Other names
- Quaternary ammonium silaneK21 antimicrobialK-21 antimicrobialK 21 antimicrobialFiteBac 2% K21 QAS
02
Targets
MMP2 (Matrix metalloproteinase-2)SrtA (Sortase A)MMP9 (Matrix metalloproteinase-9)
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