Drug intelligence / Profile preview

Flavin mononucleotide

Development stage
Approved
Modality
Small Molecules
Administration
Intravenous, Intramuscular, Oral, Ophthalmic
01

Overview

Flavin mononucleotide (FMN), also known as riboflavin 5′‑phosphate, is a biomolecule derived from the phosphorylation of vitamin B2 (riboflavin) by the enzyme riboflavin kinase. It serves as a coenzyme and prosthetic group for various oxidoreductases, including NADH dehydrogenase, and acts as a cofactor in biological blue-light photoreceptors. FMN participates in reversible redox reactions involving one or two electron transfers and is more soluble than its precursor, riboflavin. Clinically, it is used to restore or supplement vitamin B2 levels in conditions such as anemia, migraine, alcoholism, and hyperhomocysteinemia. In addition to its metabolic roles in humans and other organisms, FMN is also used as an orange-red food color additive (E101a)[1][3][4][5].

Brand names
FortaplexInfuviteInfuvite PediatricMvi PediatricNeo-bexPhotrexa
Other names
riboflavin 5'-(dihydrogen phosphate)riboflavin 5'-monophosphateriboflavin 5'-phosphateriboflavin monophosphateriboflavin phosphateriboflavin-5-phosphateriboflavin5-phosphateriboflavin 5-phosphateriboflavine dihydrogen phosphatevitamin B2 (riboflavin 5-phosphate)vitamin B2 phosphate
02

Targets

ND1 (Mitochondrial electron transport chain complex I)

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