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Flavoxine is a patented, natural dietary supplement ingredient developed by Next Pharmaceuticals designed to support cardiovascular health. It is a proprietary combination of two botanical extracts: a proprietary extract of *Phellodendron amurense* bark and a patented extract of *Citrus sinensis* (orange) peel standardized for polymethoxylated flavones (PMFs). Clinical research indicates that Flavoxine significantly improves lipid profiles by reducing LDL-cholesterol and triglycerides while increasing HDL-cholesterol. Furthermore, it has demonstrated the ability to lower blood pressure, fasting blood glucose, and C-reactive protein (CRP), a key marker of systemic inflammation. It is marketed as a nutraceutical ingredient for inclusion in heart health formulations rather than as a prescription pharmaceutical drug.
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