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Drug intelligence / Profile preview
Fli-HA platform-based gynecology product
- Development stage
- Preclinical
- Lead developer
- Fount Bio
- Modality
- Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
- Administration
- Intravaginal, Topical
01
Overview
Fli-HA is a proprietary technology platform developed by Fount Bio that utilizes bioorthogonal chemistry to create durable forms of hyaluronic acid (HA) for medical applications. The core innovation allows tailored placement and extended retention of large glycopolymers like HA on or within tissues. While the lead clinical product is Flī-Derm for dermatology, the company has an active pipeline developing similar products for ophthalmology and gynecology indications. The mechanism involves building stable HA matrices at targeted tissue sites, potentially improving local tissue hydration, repair, or barrier function. The primary developer is Fount Bio[1][2].
- Other names
- Fli-HA platform-based gynecology productFlī-HA technology platform
02
Targets
CD44 (CD44 antigen)STAB2 (Stabilin-2)ICAM1 (Intercellular Adhesion Molecule 1)LYVE1 (Lymphatic vessel endothelial hyaluronic acid receptor 1)RHAMM (Hyaluronan-mediated motility receptor)
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