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Fli-HA platform-based ophthalmology product
- Development stage
- Preclinical
- Lead developer
- Fount Bio
- Modality
- Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
- Administration
- Ophthalmic, Intravitreal, Subconjunctival
01
Overview
The Fli-HA platform-based ophthalmology product is an investigational drug delivery system developed by Fount Bio. It utilizes the proprietary Flī-HA™ technology, which is based on bioorthogonal chemistry and glycopolymer science to create durable forms of hyaluronic acid (HA) for medical applications. The core mechanism involves enabling tailored placement and prolonged retention of large glycopolymers like HA onto or within ocular tissues, potentially improving drug residence time, controlled release, and tissue hydration in the eye. This approach aims to overcome key challenges in delivering therapeutics for various ocular diseases by leveraging HA’s biocompatibility, viscoelasticity, and mucoadhesive properties[1][2][3]. While specific indications are not yet disclosed for this particular product, HA-based platforms are widely researched for conditions such as dry eye syndrome, glaucoma, retinal disorders, and ocular infections.
- Other names
- Flī-HA ophthalmology product
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