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FLR-101
- Development stage
- Preclinical
- Lead developer
- Felix Biotechnology
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
FLR-101 is an engineered yeast strain developed as a live biotherapeutic product. Its primary function is to produce enzymes that locally degrade specific antibiotics in the gut, thereby managing and mitigating the impact of antibiotics on the gut microbiome. This approach aims to protect beneficial gut bacteria during antibiotic therapy by breaking down residual antibiotics before they can disrupt the microbial community. The drug represents a novel strategy for preserving microbiome health during or after antibiotic use[1].
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