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Flu Seasonal mRNA Formulation 4
- Development stage
- Unknown
- Lead developer
- Moderna
- Modality
- mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
Flu Seasonal mRNA Formulation 4 is an investigational intramuscular multivalent seasonal influenza mRNA vaccine formulation evaluated by GSK in its GSK4382276A clinical development programme. The lipid-formulated mRNA vaccine is intended to induce immune responses against influenza viral surface antigens, including hemagglutinin and neuraminidase, to prevent seasonal influenza. Formulation 4 was one of multiple candidate formulations studied in the completed Phase 1/2 dose-finding study NCT05823974; publicly available sources do not disclose its complete strain composition or precise mRNA dose composition. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05823974))
- Other names
- Flu mRNA (GSK4382276A) formulation 4Flu Seasonal mRNA Formulation 4
02
Targets
HA (Hemagglutinin)Neuraminidase
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