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Fluarix Tetra + Vaxigrip Tetra + Fluquadri + Fluad Quad + Afluia Quad + Flucelvax Quad-University of Melbourne-influenza-COVID-19

Development stage
Unknown
Lead developer
University of Melbourne
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

This entry refers to a specific collection of vaccines evaluated in a longitudinal cohort study led by the University of Melbourne (NCT03275311). The study investigates the immunological consequences of repeated annual influenza vaccination and the impact of SARS-CoV-2 infection or vaccination on healthcare workers. The influenza component includes several quadrivalent vaccines: Fluarix Tetra (GSK), Vaxigrip Tetra (Sanofi), Fluquadri (Sanofi), Fluad Quad (adjuvanted, CSL Seqirus), Afluria Quad (CSL Seqirus), and Flucelvax Quad (cell-culture derived, CSL Seqirus). The COVID-19 component involves the administration of Comirnaty (Pfizer/BioNTech) or Vaxzevria (AstraZeneca). These vaccines function by inducing active immunity against specific viral antigens—hemagglutinin for influenza and the spike protein for SARS-CoV-2—to elicit protective antibody and cellular immune responses.

Brand names
Afluria QuadFlucelvax QuadComirnatyVaxzevria
Other names
Afluria Quad
02

Targets

SARS-CoV-2 spikeHA (Hemagglutinin)

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