Drug intelligence / Profile preview

Fludarabine + Carmustine + Melphalan

Development stage
Preclinical
Lead developer
Suzhou Hongci Hematology Hospital
Modality
Small Molecules
Administration
Intravenous
01

Overview

Fludarabine + Carmustine + Melphalan (FBMA) is a reduced intensity conditioning (RIC) regimen used prior to allogeneic hematopoietic stem cell transplant in patients with myelogenous leukemia. This combination chemotherapy aims to suppress the patient's immune system to prevent graft rejection and to eradicate residual malignant cells, thereby preparing the bone marrow for the engraftment of donor stem cells.

Other names
FBMA方案
02

Targets

DNA

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