Drug intelligence / Profile preview

flunixin

Development stage
Unknown
Modality
Small Molecules
Administration
Intravenous, Intramuscular, Oral
01

Overview

Flunixin is a **small molecule nonsteroidal anti-inflammatory drug** used primarily in veterinary medicine. It acts by inhibiting **cyclooxygenase enzymes**, reducing prostaglandin synthesis and thereby providing **analgesic, antipyretic, and anti-inflammatory** effects. In practice it is commonly administered as **flunixin meglumine** and is approved for use in animals including **horses, cattle, and pigs**. Major labeled uses include treatment of pain and inflammation associated with **musculoskeletal disorders** and **colic in horses**, and control of **pyrexia associated with bovine respiratory disease**, **endotoxemia**, and **acute bovine mastitis** in cattle. It is marketed as a prescription veterinary medicine, including under the brand name **Banamine**, and is manufactured by companies including **Norbrook**.

Brand names
Banamine
Other names
flunixin meglumine
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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