Drug intelligence / Profile preview

fluorometholone

Development stage
Approved
Lead developer
Allergan
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Ophthalmic, Topical
01

Overview

Fluorometholone is a synthetic glucocorticoid corticosteroid primarily used as an ophthalmic suspension to treat inflammation of the eye caused by surgery, injury, or other conditions. It acts by inhibiting the inflammatory response in ocular tissues such as the conjunctiva and cornea. The drug reduces swelling by suppressing immune system activity and limiting processes like edema formation, leukocyte migration, capillary dilation and proliferation, fibroblast proliferation, collagen deposition, and scar formation. Fluorometholone is available only with a prescription and is supplied under several brand names for topical ophthalmic use. Developed and manufactured by Allergan, fluorometholone exerts its effects by acting as an agonist of the glucocorticoid receptor.

Brand names
FlarexFML Forte LiquifilmFML LiquifilmFML S.O.P.Fluor-OpEflone
Other names
flumetholon
02

Targets

GR (Glucocorticoid receptor)

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