fluoxetine + lovastatin + omeprazole + caffeine + midazolam + dextromethorphan

This is a combination product containing six active pharmaceutical ingredients: fluoxetine, lovastatin, omeprazole, caffeine, midazolam, and dextromethorphan. Each component has a distinct mechanism of action and therapeutic use: - **Fluoxetine** is a selective serotonin reuptake inhibitor (SSRI) used primarily as an antidepressant. - **Lovastatin** is an HMG-CoA reductase inhibitor (statin) used to lower cholesterol. - **Omeprazole** is a proton pump inhibitor that suppresses gastric acid secretion by irreversibly inhibiting the H^+/K^+-ATPase enzyme in gastric parietal cells[1][2][5]. - **Caffeine** is a central nervous system stimulant that acts as an adenosine receptor antagonist. - **Midazolam** is a short-acting benzodiazepine with anxiolytic, amnestic, hypnotic, anticonvulsant, and muscle relaxant properties; it acts primarily via potentiation of GABA_A receptors. - **Dextromethorphan** is an antitussive agent acting on the central nervous system as an NMDA receptor antagonist and sigma-1 receptor agonist[6]. This specific combination does not correspond to any known approved or marketed pharmaceutical product; rather it represents the co-administration of these six drugs.

Other names

University of Washington CYP probe cocktailFluoxetine CYP interaction cocktailNCT01361217 cocktailNCT-01361217 cocktailNCT 01361217 cocktail