Drug intelligence / Profile preview

Fluoxetine + Valsartan

Development stage
Phase 4
Lead developer
Eli Lilly
Modality
Drug Delivery Systems
Administration
Oral
01

Overview

The combination of fluoxetine and valsartan is not a standard fixed-dose combination drug with its own brand name. Rather, it represents two separate medications that may be prescribed together or taken concurrently by patients. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant used to treat conditions like major depressive disorder, obsessive-compulsive disorder, bulimia nervosa, panic disorder, and bipolar I disorder. It's commonly known by the brand name Prozac. Valsartan is an angiotensin II receptor blocker (ARB) used to treat hypertension (high blood pressure), heart failure, and to reduce the risk of death after heart attack. It's commonly known by the brand name Diovan. When taken together, these medications may interact. Fluoxetine may increase the blood levels and effects of amlodipine (which is often combined with valsartan in products like Exforge). This suggests there could be potential interactions between fluoxetine and valsartan as well, though specific information about this exact combination is limited in the provided search results. Patients taking both medications should be aware of potential side effects and interactions. Healthcare providers should carefully monitor patients on this combination and may need to adjust dosages accordingly.

02

Targets

AGTR1 (Angiotensin II Type-1 receptor)SERT (Sodium-dependent serotonin transporter)

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