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fluphenazine
- Development stage
- Approved
- Lead developer
- Bristol Myers Squibb
- Modality
- Small Molecules
- Administration
- Oral, Intramuscular
01
Overview
Fluphenazine is a first-generation (typical) antipsychotic medication belonging to the phenothiazine class. It is primarily used to treat schizophrenia and other psychotic disorders by rebalancing dopamine levels in the brain. The drug works by blocking dopamine receptors in the central nervous system (CNS), thereby reducing symptoms such as hallucinations and delusions[2][6][7]. It is available in oral tablet and liquid forms for daily use and as long-acting injectable formulations (fluphenazine decanoate or enanthate) for maintenance therapy[5][8].
- Brand names
- ProlixinPermitilModecateModitenRhoFluphenazine
- Other names
- FlufenazinaFluorfenazineFluorophenazineFluorphenazineFluphenazinFluphénazineFluphenazinumTriflumethazine
02
Targets
DRD1 (Dopamine D1 Receptor)DRD2 (Dopamine D2 Receptor)
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