Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
flurbiprofen axetil
- Development stage
- Approved
- Lead developer
- Kaken Pharmaceutical
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Administration
- Intravenous
01
Overview
Flurbiprofen axetil is a prodrug of flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID) belonging to the propionic acid class. After administration, it is hydrolyzed by esterases in the blood to release active flurbiprofen. The active form inhibits cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing prostaglandin synthesis and exerting anti-inflammatory and analgesic effects. Flurbiprofen axetil has been investigated for its use in pain management, particularly perioperative pain and rheumatoid arthritis. It is formulated as an injectable preparation to improve solubility and pharmacokinetics compared to oral flurbiprofen[1][3][5].
- Brand names
- RopionLipfen
- Other names
- 1-Acetoxyethyl 2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoate91503-79-6
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)
Beyond the preview
Go deeper on flurbiprofen axetil.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on flurbiprofen axetil.