Drug intelligence / Profile preview

folic acid + vitamin B12 + vitamin B6 + rosuvastatin

Development stage
Unknown
Lead developer
Copka Sonpashan
Modality
Drug Delivery Systems
Administration
Oral
01

Overview

This is a combination medication that includes B vitamins (folic acid, vitamin B12, and vitamin B6) along with **rosuvastatin**, which is a statin medication used to lower cholesterol levels. The B-group vitamin supplementation (including folic acid, vitamin B12, and B6) can be used alongside statin therapy (like rosuvastatin) to improve endothelial function in **cardiovascular patients**. This combination appears to have an additive effect on improving endothelial function, with the B vitamins primarily working by reducing homocysteine levels while rosuvastatin works by reducing LDL-cholesterol and through pleiotropic effects. Rosuvastatin (brand name Crestor) is an HMG-CoA reductase inhibitor that lowers lipid levels and reduces cardiovascular disease risk. It's indicated for treating various lipid disorders and preventing major cardiovascular events in patients with risk factors. The B vitamin combination (folic acid, vitamin B12, and vitamin B6) appears to be similar to products like Folgard, Foltx, and Homocysteine Formula, which are used to provide these essential B vitamins. These vitamins, particularly folic acid, may help decrease homocysteine concentrations, which is beneficial for cardiovascular health. This combination appears to be designed to address both cholesterol management (via rosuvastatin) and homocysteine reduction (via B vitamins) for comprehensive cardiovascular risk management.

Other names
rosuvastatin and B-vitamins
02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)

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