Drug intelligence / Profile preview

folic acid + vitamin B6 + vitamin C + vitamin E

Development stage
Unknown
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

This is a combination dietary supplement containing four essential vitamins: folic acid (vitamin B9), vitamin B6 (pyridoxine), vitamin C (ascorbic acid), and vitamin E (tocopherol). Each component plays a distinct role in human health. Folic acid is crucial for DNA synthesis, cell division, and prevention of neural tube defects; it also helps lower homocysteine levels[7][5][6]. Vitamin B6 acts as a coenzyme in amino acid metabolism, neurotransmitter synthesis, and supports one-carbon metabolism alongside folate[2][3][5][6]. Vitamin C functions as an antioxidant, aids collagen synthesis, enhances iron absorption, and supports immune function. Vitamin E is a fat-soluble antioxidant that protects cell membranes from oxidative damage. This combination is typically used to prevent or treat deficiencies due to poor diet or increased requirements during pregnancy or illness[1]. It may also be marketed for cardiovascular support by lowering homocysteine levels; however, evidence for reduction of cardiovascular events with such supplementation remains inconclusive[5].

02

Targets

DHFR (Dihydrofolate reductase)P4H (Prolyl 4-hydroxylase subunit alpha-3)

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