Drug intelligence / Profile preview

follicle stimulating hormone + luteinizing hormone + cetrorelix

Development stage: Unknown
Lead developer: Ceapro
Modality: Recombinant Proteins and Enzymes, Small Molecules
Administration: Subcutaneous

Overview

This is a combination therapy used in assisted reproductive technologies (ART), specifically for controlled ovarian stimulation. The protocol combines gonadotropins (FSH and LH, often administered as human menopausal gonadotropin or recombinant FSH) with cetrorelix, a GnRH antagonist. FSH and LH stimulate follicular growth and development, while cetrorelix prevents premature LH surges by blocking GnRH receptors on pituitary cells. This controlled approach allows for proper follicular maturation before triggering ovulation with human chorionic gonadotropin (hCG).

Targets

FSHR (Follicle-stimulating hormone receptor)GnRHR (Gonadotropin-releasing hormone receptor)LHCGR (Luteinizing hormone/choriogonadotropin receptor)

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