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Drug intelligence / Profile preview
follicle stimulating hormone + luteinizing hormone + cetrorelix
- Development stage
- Unknown
- Lead developer
- Ceapro
- Modality
- Small Molecules, Recombinant Proteins and Enzymes
- Administration
- Subcutaneous
01
Overview
This is a combination therapy used in assisted reproductive technologies (ART), specifically for controlled ovarian stimulation. The protocol combines gonadotropins (FSH and LH, often administered as human menopausal gonadotropin or recombinant FSH) with cetrorelix, a GnRH antagonist. FSH and LH stimulate follicular growth and development, while cetrorelix prevents premature LH surges by blocking GnRH receptors on pituitary cells. This controlled approach allows for proper follicular maturation before triggering ovulation with human chorionic gonadotropin (hCG).
02
Targets
FSHR (Follicle-stimulating hormone receptor)GnRHR (Gonadotropin-releasing hormone receptor)LHCGR (Luteinizing hormone/choriogonadotropin receptor)
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