Drug intelligence / Profile preview

folliculi sennae ethanol extract

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

Folliculi sennae ethanol extract is a plant-derived extract obtained from the pods (fruit) of the Senna plant (typically *Senna alexandrina*). While Senna is traditionally known for its laxative properties due to sennosides, this specific ethanol extract has been investigated for its multifunctional potential in treating Alzheimer's disease and type 2 diabetes mellitus. It contains bioactive phenolic compounds such as quercetin, luteolin, kaempferol, and gallic acid. The extract demonstrates antioxidant activity and acts as an inhibitor of key enzymes including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and alpha-glucosidase. By modulating oxidative stress and inhibiting these enzymes, it aims to provide neuroprotective and glucose-regulating effects.

Other names
Senna pod ethanol extractSenna fruit ethanol extractFolliculi sennae extract
02

Targets

Sucrase-IsomaltaseButyrylcholinesteraseAcetylcholinesterase

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