Drug intelligence / Profile preview

Follistatin gene therapy (Integrated Health Systems)

Development stage
Preclinical
Lead developer
Integrated Healthcare Systems
Modality
Gene Therapies
Administration
Intramuscular
01

Overview

Integrated Health Systems (IHS) offers a follistatin gene therapy designed to preserve muscle strength, function, and metabolic health by preventing age-related physical decline. The therapy works by overexpressing follistatin, a secreted protein that acts as a potent antagonist to myostatin (a protein that naturally limits muscle growth) and modulates activin signaling. By inhibiting these negative regulators of muscle mass, the therapy aims to promote muscle hypertrophy, enhance regeneration, and reduce inflammation. IHS positions this as part of its anti-aging and regenerative medicine portfolio, offering it as a concierge medical service rather than a drug in traditional clinical development phases.

Other names
Follistatin (FST) overexpressionFST gene therapyIntegrated Health Systems Follistatin Gene Therapy
02

Targets

NODAL (Nodal growth differentiation factor)GDF8 (Myostatin)Activin A

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