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US Biologic is developing an oral vaccine for Foot and Mouth Disease (FMD) utilizing its proprietary OrisBio platform. This technology employs *Bacillus subtilis* (*B. subtilis*) spores as a delivery vehicle to express Foot-and-Mouth Disease Virus (FMDV) antigens. The vaccine is designed for oral administration to livestock, where the spores facilitate the delivery of antigens to the mucosal immune system to elicit protective immunity. The program is currently in the preclinical stage and is being developed in collaboration with the Department of Homeland Security (DHS) Plum Island Animal Disease Center.
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