foot-and-mouth disease virus synthetic peptide vaccine

The **foot-and-mouth disease virus synthetic peptide vaccine** is a veterinary vaccine developed by **Shen Lian Biotech** for the prevention of Foot-and-Mouth Disease (FMD) in livestock, particularly swine and cattle. It represents a significant technological milestone as the first synthetic peptide vaccine for FMD to be commercialized globally. The vaccine is composed of chemically synthesized peptides that mimic the immunodominant epitopes of the Foot-and-Mouth Disease Virus (FMDV) capsid protein, specifically the G-H loop of the VP1 protein. Unlike traditional inactivated vaccines, this synthetic approach eliminates the risk of incomplete virus inactivation or virus escape during the manufacturing process. Furthermore, it allows for the **Differentiation of Infected from Vaccinated Animals (DIVA)**, as the vaccine only contains specific viral peptides rather than the full array of viral proteins. It is approved in China and has been widely utilized in national compulsory immunization programs to control FMD outbreaks.

Brand names

Shen Lian

Other names

口蹄疫合成肽疫苗FMD synthetic peptide vaccineFoot-and-mouth disease virus type O synthetic peptide vaccineKoutiyi Hechengtai Yimiao