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Fornerve NT
- Development stage
- Unknown
- Lead developer
- Cachet Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Fornerve NT is a fixed-dose combination pharmaceutical formulation developed by Cachet Pharmaceuticals for the management of neuropathic pain. It contains three active ingredients: pregabalin, an anticonvulsant that binds to the alpha-2-delta subunit of voltage-gated calcium channels; nortriptyline, a tricyclic antidepressant that inhibits the reuptake of norepinephrine and serotonin; and methylcobalamin, a form of vitamin B12 that aids in the regeneration of the myelin sheath and nerve cell protection. This combination is designed to provide 24-hour pain relief with once-daily dosing by addressing both the symptoms and the underlying nerve damage associated with various forms of neuropathy.
- Brand names
- Fornerve NT
- Other names
- pregabalin + nortriptyline + methylcobalamin
02
Targets
MTR (Methionine synthase)NET (Norepinephrine Transporter)SERT (Sodium-dependent serotonin transporter)CACNA2D1 (Voltage-gated calcium channel subunit alpha2/delta-1)
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