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FOXC1 siRNA
- Development stage
- Preclinical
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Intravenous, Intraperitoneal
01
Overview
FOXC1 siRNA is a research-stage small interfering RNA (siRNA) molecule designed to silence the expression of the Forkhead Box C1 (FOXC1) transcription factor. It functions through the RNA interference (RNAi) pathway, where the siRNA duplex mediates the sequence-specific degradation of FOXC1 mRNA, thereby reducing protein levels. Preclinical studies have investigated its potential in various malignancies, including pancreatic cancer, non-small cell lung cancer, and hepatocellular carcinoma, where it has been shown to inhibit cell proliferation, migration, and invasion. It is primarily utilized as a molecular biology tool in academic research to study FOXC1-related signaling pathways and explore its viability as a therapeutic target.
- Other names
- si-FOXC1si-FOXC-1si-FOXC 1FOXC1 small interfering RNAFOXC-1 small interfering RNAFOXC 1 small interfering RNA
02
Targets
FOXC1
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