Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
FP-TZTP
- Development stage
- Preclinical
- Lead developer
- National Institute of Mental Health
- Modality
- Alpha Emitters → Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Beta Emitters → Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
- Administration
- Intravenous
01
Overview
FP-TZTP is a small molecule muscarinic acetylcholine receptor agonist with high selectivity for the M2 subtype. It is primarily used as a radioligand in positron emission tomography (PET) imaging to study muscarinic M2 receptor distribution and function in the brain. The compound can be labeled with fluorine‑18 ([18F]FP-TZTP) or carbon‑11 for PET studies. Its main research application is in neurodegenerative diseases such as Alzheimer's disease, where it enables noninvasive measurement of cholinergic system integrity and function[1][7][10]. FP-TZTP binds selectively to M2 receptors and its binding can be competitively inhibited by endogenous acetylcholine or other muscarinic agonists[6][10]. It does not have approved therapeutic indications but serves as an important tool compound for neuroscience research.
- Other names
- 424829-90-3C2LNI0YP8ZC-2LNI0YP8ZC 2LNI0YP8ZUNII-C2LNI0YP8ZUNII-C-2LNI0YP8ZUNII-C 2LNI0YP8ZDTXSID50435762DTXSID-50435762DTXSID 50435762
02
Targets
CHRM2 (M2)M1 (Muscarinic acetylcholine receptor M1)
Beyond the preview
Go deeper on FP-TZTP.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on FP-TZTP.