Drug intelligence / Profile preview

FP0011

Development stage
Unknown
Lead developer
Domain Therapeutics
Modality
Small Molecules
01

Overview

FP0011 is a small molecule antiglutamatergic compound developed for its symptomatic and disease-modifying effects in neurological disorders such as amyotrophic lateral sclerosis (ALS) and Parkinson's disease. It acts as an antagonist of metabotropic glutamate receptors (mGluRs), modulating presynaptic glutamate release and providing neuroprotective properties. The drug has been investigated primarily for its potential to treat ALS and Parkinson's disease by reducing excitotoxicity mediated by excessive glutamate signaling[1][2][4].

02

Targets

mGluR (Metabotropic glutamate receptors)

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