Drug intelligence / Profile preview

FR230513

Development stage
Unknown
Lead developer
Astellas Pharma
Modality
Small Molecules
01

Overview

FR230513 is an experimental small molecule compound belonging to the class of organic compounds known as naphthalenes. It acts as a potent non-nucleoside inhibitor of adenosine deaminase (ADA), with reported high affinity (Ki = 7.7 nM). The compound has been studied in pharmacology and molecular biology for its potential therapeutic applications but has not advanced beyond preclinical or early research stages. Its chemical formula is C18H19N3O2 and it is structurally characterized by a naphthalene moiety linked to an imidazole carboxamide[1][2][9].

Other names
1-[(2R)-1-hydroxy-4-(naphthalen-1-yl)butan-2-yl]-1H-imidazole-4-carboxamide1ndy1-((1R)-1-(hydroxymethyl)-3-(1-naphthyl)propyl)-1H-imidazole-4-carboxamide
02

Targets

ADA (Adenosine deaminase)

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