framycetin sulfate

Framycetin sulfate is an aminoglycoside antibiotic, specifically neomycin B, primarily used for the topical treatment of bacterial infections. It exerts its antibacterial effect by binding to the 30S subunit of the bacterial ribosome, which inhibits protein synthesis and leads to the misreading of the genetic code. In clinical practice, it is frequently utilized in medicated dressings (such as Sofratulle) to prevent postoperative wound infection and promote healing, particularly in surgical procedures like palatoplasty for cleft palate. It is manufactured by several companies, including Darya-Varia Laboratory and Sanofi.

Brand names

SoframycinSofratulle

Other names

framicetyn sulfateframycetinneomycin B sulfate