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**FREE-002** is an investigational ketamine-based neuropsychiatric therapeutic program developed by Freedom Biosciences for **comorbid major depressive disorder and substance use disorder**. The program is intended to preserve ketamine-associated antidepressant activity while reducing addiction liability. Freedom Biosciences' public pipeline places FREE-002 in Phase 2 and identifies it as one of the company's clinical-data-supported programs. The precise composition, formulation, route of administration, and mechanism beyond its ketamine-based pharmacology have not been publicly disclosed.
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