Drug intelligence / Profile preview

FREE008

Development stage
Preclinical
Lead developer
Freedom Biosciences
Modality
Small Molecules
01

Overview

**FREE008** is an investigational neuropsychiatric combination-drug program developed by Freedom Biosciences for **major depressive disorder**. Freedom Biosciences described it as a non-hallucinogenic psilocybin program expected to enter a UK Phase 1 study in 2025; a later industry pipeline tracker identifies the program as a combination of psilocybin and an undisclosed phosphodiesterase 9 inhibitor. ([youtube.com](https://www.youtube.com/watch?v=Pd1whzFX26A))

02

Targets

HTR2A (Serotonin receptor 5-HT2A)

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