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freeze-dried capsulized fecal microbiota transplantation
- Development stage
- Unknown
- Lead developer
- Jinling Hospital
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
A freeze-dried, encapsulated formulation of fecal microbiota transplantation (FMT) developed by Jinling Hospital, China, specifically for treating relapsing Clostridium difficile infection (RCDI). This product is being investigated as a less invasive and more convenient alternative to traditional FMT administration methods, such as colonoscopy or nasojejunal tube. [6] The underlying principle is to restore a healthy gut microbial balance, which in turn suppresses the pathogenic C. difficile, thereby resolving the infection. [4, 5]
- Other names
- fecal microbiota transplantFMTfecal microbiota transplantation-Jinling Hospital, China-Clostridium difficile infectionFreeze-dried, Capsulized Fecal Microbiota Transplantation
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