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freeze-dried rabies vaccine (Vero cells)
- Development stage
- Phase 3
- Lead developer
- Anhui Zhifei Longcom Biopharmaceutical
- Modality
- Whole Inactivated Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
Freeze-dried rabies vaccine (Vero cells) is an inactivated biological product developed by Anhui Zhifei Longcom Biopharmaceutical, a subsidiary of Chongqing Zhifei Biological Products, for the prevention of rabies in humans. The vaccine is produced by culturing the rabies virus in Vero cells, followed by inactivation and lyophilization (freeze-drying) to ensure stability. It is intended for post-exposure prophylaxis to induce the production of protective neutralizing antibodies against the rabies virus. The vaccine is administered via intramuscular injection after reconstitution and has been evaluated in clinical trials using standard immunization schedules, including the 5-dose Essen regimen and the 4-dose Zagreb regimen. It is designed to meet a potency requirement of not less than 2.5 IU per dose.
- Brand names
- Zhifeilongkoma
- Other names
- Freeze-Dried Rabies Vaccine for Human Use (Vero Cells)freeze-dried rabies vaccine (Vero cells)-Anhui Zhifei Longcom Biopharmaceutical-inactivated vaccine-rabies
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