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Fresenius Conventional Peritoneal Dialysis Solution

Development stage
Unknown
Lead developer
Fresenius Medical Care
Modality
Small Molecules
Administration
Intraperitoneal
01

Overview

The conventional peritoneal dialysis (PD) solution from Fresenius Medical Care is a standard-of-care dialysis fluid used for the management of chronic renal failure. These solutions are typically glucose-based and are characterized by an acidic pH (approximately 5.5) and the presence of glucose degradation products (GDPs), which result from the heat-sterilization process. They function by being introduced into the peritoneal cavity, where the high glucose concentration creates an osmotic gradient that draws excess water and uremic toxins from the blood across the peritoneal membrane. These solutions are available in various formulations (e.g., CAPD 2, CAPD 17) with differing glucose and calcium concentrations to meet individual patient needs. While effective for renal replacement therapy in both Continuous Ambulatory Peritoneal Dialysis (CAPD) and Automated Peritoneal Dialysis (APD), they are often used as clinical trial comparators for newer biocompatible solutions that aim to better preserve the peritoneal membrane and residual renal function.

Brand names
CAPD 2CAPD2CAPD-2CAPD 3CAPD3CAPD-3CAPD 4CAPD4CAPD-4CAPD 17CAPD17CAPD-17CAPD 18CAPD18CAPD-18CAPD 19CAPD19CAPD-19
Other names
Standard PD solutionTraditional PD solutionAcidic PD solutionFresenius CAPD/APD solution

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