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fresh fecal microbiota transplant

Development stage: Unknown
Lead developer: BiomeBank
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Colonoscopy, Enema, Nasogastric Tube, Nasoduodenal Tube

Overview

Fresh fecal microbiota transplant (FMT) is a therapeutic procedure that involves transferring fecal bacteria and other microbes from a healthy donor to a recipient. It is primarily used for treating recurrent Clostridioides difficile infection (CDI). Fresh FMT refers specifically to FMT using non-frozen stool that is processed and administered within hours of collection. The procedure works by restoring gut microbiota diversity, which helps combat C. difficile by reestablishing a healthy bacterial community in the intestine. Fresh FMT can be administered through various routes including colonoscopy, enema, nasogastric tube, or nasoduodenal tube.

Other names: Fresh FMTfresh stool transplant

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