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Frovatriptan is a small molecule pharmaceutical drug used for the acute treatment of migraine headaches in adults, with or without aura. It belongs to the triptan class (selective serotonin receptor agonists) and acts primarily as an agonist at serotonin 5-HT1B and 5-HT1D receptors. Its mechanism of action involves narrowing blood vessels around the brain, inhibiting excessive vasodilation, blocking pain signal transmission in the trigeminal pathway, and reducing release of substances that cause migraine symptoms such as pain, nausea, and sensitivity to light or sound. Frovatriptan is notable for its long half-life among triptans (~26 hours), which may contribute to sustained relief. It does not prevent migraines or reduce their frequency[1][2][4][6].
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