Drug intelligence / Profile preview

FT-018

Development stage
Preclinical
Lead developer
Frontera Therapeutics
Modality
Gene Therapies
01

Overview

**FT-018** is an investigational recombinant adeno-associated virus gene therapy being developed by Fronterra for **arrhythmogenic right ventricular cardiomyopathy**. It is listed in the company's cardiovascular pipeline as a **preclinical** program. The specific transgene, molecular target, and detailed mechanism of action have not been publicly disclosed, but the therapeutic concept is gene replacement or gene delivery using an rAAV vector for a genetic cardiomyopathy indication. Fronterra has also indicated preclinical research progress for FT-018 at the 2025 ASGCT Annual Meeting and uses a proprietary insect-cell-based rAAV manufacturing platform for its gene therapy programs.

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