Drug intelligence / Profile preview

Fu-Zheng-Qu-Zhuo

Development stage
Phase 3
Administration
Oral
01

Overview

Fu-Zheng-Qu-Zhuo (FZQZ) is a traditional Chinese medicine (TCM) formulation primarily used as an adjunct therapy for patients with stage 3–4 chronic kidney disease (CKD). It is typically administered as an oral liquid and is often combined with standard integrated therapies. Clinical studies have shown that FZQZ can slow the progression of CKD, reduce the occurrence of composite endpoint events such as initiation of dialysis, doubling of serum creatinine, or CKD-related death, and improve patient-reported symptoms like appetite and physical function. The mechanism of action is not fully elucidated but may involve improving liver and spleen function to enhance organic immunity. Common herbal components include rhubarb (dahuang), Astragalus membranaceus (huangqi), and Angelica sinensis (danggui)[1][2][3][5]. Safety data indicate no significant increase in adverse events compared to placebo[1].

Brand names
Fu-Zheng-Qu-Zhuo oral liquid
Other names
Fu-Zheng-Qu-Zhuo methodFZQZ oral liquid

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