Drug intelligence / Profile preview

Fudan Univ. TLR2 compound B12

Development stage
Unknown
Lead developer
Fudan University
01

Overview

Fudan Univ. TLR2 compound B12: sourced facts only. name: "Among them, diastereomer B10 and B12 substituted (S)-2-phenylcyclopropylamide side chain of Diprovocim with simple (R)- and (S)-n-butyl groups exhibited comparable TLR2 agonistic activities with EC50 values of 35 nM and 39 nM, respectively." [PMID:36174413]; target: "Among them, diastereomer B10 and B12 substituted (S)-2-phenylcyclopropylamide side chain of Diprovocim with simple (R)- and (S)-n-butyl groups exhibited comparable TLR2 agonistic activities with EC50 values of 35 nM and 39 nM, respectively." [PMID:36174413]; developer: "Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China." [PMID:36174413]

02

Targets

TLR2 (Toll-like Receptor 2)

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