fufang changtai granules

Fufang Changtai Granules is a Traditional Chinese Medicine (TCM) compound developed by the Second Military Medical University (SMMU), specifically within the Department of Gastroenterology at Changhai Hospital. It is primarily indicated for the treatment of ulcerative colitis (UC), particularly for patients presenting with damp-heat and spleen deficiency patterns. The formulation is a complex mixture of herbal extracts, typically including *Astragalus membranaceus* (Huangqi), *Coptis chinensis* (Huanglian), *Sanguisorba officinalis* (Diyu), *Curcuma wenyujin* (Yujin), and *Paeonia lactiflora* (Baishao). Its mechanism of action involves the suppression of intestinal inflammation through the inhibition of the NF-κB signaling pathway and the subsequent downregulation of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. Clinical studies conducted in China have demonstrated its efficacy in inducing clinical remission and promoting mucosal healing in patients with mild-to-moderate ulcerative colitis.

Brand names

Changtai Granules

Other names

Compound Changtai GranulesChangtai Keli