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fufang congrong yizhi
- Development stage
- Phase 4
- Lead developer
- Lei Yun Shang
- Administration
- Oral
01
Overview
Fufang Congrong Yizhi is a traditional Chinese medicine compound formulation used primarily for the treatment of cognitive impairment and vascular dementia. It is available as capsules and contains multiple herbal ingredients including Cistanches Herba (Cistanche deserticola), Polygoni Multiflori Radix Praeparata (processed Polygonum multiflorum root), Folium nelumbinis (lotus leaf), Pheretima (earthworm extract), and Rhapontici Radix. The mechanism of action is believed to involve neuroprotection, improvement of cerebral blood flow, anti-inflammatory effects, and reduction of β-amyloid-induced neuronal damage. Preclinical studies suggest it may reduce MARCKS mRNA levels in the hippocampus in dementia models[6]. It has been licensed for mild to moderate vascular dementia with symptoms such as stasis obstructing brain collaterals and blood stasis-phlegm[5]. Adverse effects can include drug-induced liver injury[2].
- Brand names
- Fufang Congrong Yizhi CapsulesFCYCCCYC
- Other names
- Compound Congrong Yizhi CapsulesFu Fang Cong Rong YiZhiCong Sheng Capsule
02
Targets
BAX (Apoptosis regulator BAX)
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