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Fufang Ejiao Jiang
- Development stage
- Unknown
- Lead developer
- Dong-E-E-Jiao
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Fufang Ejiao Jiang (also known as Compound Ejiao Syrup) is a traditional Chinese medicine (TCM) oral solution developed and manufactured by Dong-E E-Jiao. It is approved in China by the National Medical Products Administration (NMPA) for replenishing Qi and nourishing blood, and is widely used to treat symptoms of Qi and blood deficiency, including anemia, leukopenia, dizziness, insomnia, and fatigue. The formulation is a complex herbal mixture composed of Ejiao (Asini Corii Colla / donkey-hide gelatin), red ginseng (Ginseng Radix Rubra), Radix Rehmanniae (prepared Rehmannia root), Radix Codonopsis pilosula, and Hawthorn (Crataegi Fructus). Fufang Ejiao Jiang is currently being evaluated in Phase II clinical trials for the treatment of cancer-related fatigue (CRF) in patients with gastric or colorectal cancer undergoing postoperative adjuvant chemotherapy.
- Brand names
- Fufang Ejiao Jiang
- Other names
- Compound E'jiao JiangCompound Ejiao SyrupFufang E'jiao JiangFufang E'jiao SyrupFufang Ejiao Syrup复方阿胶浆
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)BCL2L1 (B-cell lymphoma-extra large protein)CASP3 (Caspase-3)ICAM1 (Intercellular Adhesion Molecule 1)IL1B (Interleukin-1 beta)IL-6 (Interleukin 6)mTOR (Mammalian target of rapamycin kinase)VEGFA (Vascular endothelial growth factor A)
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