Drug intelligence / Profile preview

fufang huangqi

Development stage
Unknown
Lead developer
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Modality
Peptides, Small Molecules
Administration
Oral
01

Overview

Fufang Huangqi is a Traditional Chinese Medicine (TCM) compound formulation developed by the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine specifically for the treatment of myasthenia gravis (MG). The formulation is primarily composed of *Astragalus membranaceus* (Huangqi) as the chief ingredient, which is known for its immunomodulatory and 'Qi-tonifying' properties. It is often combined with other herbs such as *Cimicifuga foetida* and *Bupleurum chinense* to address the underlying pathology of MG according to TCM principles. Mechanistically, Fufang Huangqi acts as an immunomodulator by regulating the balance of T-cell subsets (including Th1/Th2 and Th17/Treg populations) and reducing the production of pathogenic anti-acetylcholine receptor (AChR) antibodies. It is typically used as an adjunctive therapy to conventional treatments like cholinesterase inhibitors and corticosteroids to improve clinical symptoms, increase muscle strength, and reduce relapse rates in patients with MG.

Other names
Compound AstragalusFufang Huangqi TangFufang Huangqi GranulesCompound Astragalus Decoction
02

Targets

Nicotinic Acetylcholine Receptor

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