Drug intelligence / Profile preview

fufang xiaoying keli

Development stage
Unknown
Lead developer
China-Japan Friendship Hospital
Administration
Oral
01

Overview

Fufang Xiaoying Keli (Compound Xiaoying Granules) is a Traditional Chinese Medicine (TCM) compound formulation primarily utilized for the treatment of thyroid disorders such as goiter and thyroid nodules. Developed as a hospital preparation (notably by the China-Japan Friendship Hospital in Beijing), it is composed of several herbal ingredients including *Prunella vulgaris* (Xiaokuicao), *Sargassum* (Haizao), *Laminaria* (Kunbu), *Scrophularia* (Xuanshen), and *Concha Ostreae* (Muli). The formulation is designed to resolve phlegm, soften hard masses, and clear heat, addressing the TCM pathogenesis of Qi stagnation and phlegm coagulation in the thyroid. Clinically, it is used to reduce the size of benign thyroid nodules and alleviate symptoms associated with thyroid enlargement. While its precise molecular mechanisms are complex due to its multi-component nature, research suggests it may modulate thyroid hormone signaling and exert anti-inflammatory and anti-proliferative effects on thyroid tissue.

Brand names
Fufang Xiaoying
Other names
Compound Xiaoying GranulesFufang Xiaoying Granules复方消瘿颗粒
02

Targets

TSHR (Thyroid-stimulating hormone receptor)

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