Drug intelligence / Profile preview

fuling decoction + xiaochaihu decoction

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Fuling Decoction + Xiaochaihu Decoction is a combination of two classical traditional Chinese medicine (TCM) formulas. Fuling Decoction (Fuling Tang) and Xiaochaihu Decoction (Xiao Chai Hu Tang, also known as Minor Bupleurum Decoction) are both multi-herb prescriptions with distinct but sometimes complementary indications in TCM practice. - **Xiaochaihu Decoction** is composed of Bupleuri Radix (Chai Hu), Scutellariae Radix (Huang Qin), Pinelliae Rhizoma (Ban Xia), Zingiberis Rhizoma Recens (Sheng Jiang), Ginseng Radix et Rhizoma (Ren Shen), Glycyrrhizae Radix Praeparata cum Melle (Zhi Gan Cao), and Jujubae Fructus (Da Zao)[1][5][6]. It is traditionally used to harmonize the Shaoyang stage of disease, modulate immune response, reduce inflammation, and support liver function. Modern studies suggest it can modulate inflammatory pathways, induce cytochrome P450 enzymes such as CYP3A1/2, and may have anti-tumor effects[5][6]. - **Fuling Decoction** typically contains Poria cocos fungus along with other herbs such as White Atractylodes rhizome, Cinnamon twig or root bark, Licorice root among others. It is primarily used for promoting urination to drain dampness and strengthen the spleen. The combination of these two formulas would be expected to provide synergistic effects for conditions involving both Shaoyang disharmony and dampness accumulation according to TCM theory. The mechanism involves multi-target modulation including anti-inflammatory action, immunomodulation via cytokine regulation, hepatoprotective effects through reduction of liver fibrosis markers[5], possible induction of hepatic drug-metabolizing enzymes[6], and general harmonization/regulation of digestive/liver/gallbladder function.

Other names
fuling tang + xiao chai hu tangporia decoction + minor bupleurum decoction
02

Targets

IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))TP53 (Cellular Tumor Antigen p53 R175H)MAPK3 (Mitogen-activated protein kinase 1)IL1B (Interleukin-1 beta)

Beyond the preview

Go deeper on fuling decoction + xiaochaihu decoction.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on fuling decoction + xiaochaihu decoction.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call