Drug intelligence / Profile preview

fuling-zexie decoction

Development stage
Unknown
Lead developer
Guangdong Provincial Hospital of Traditional Chinese Medicine
Administration
Oral
01

Overview

Fuling-Zexie Decoction is a Traditional Chinese Medicine (TCM) herbal formula primarily composed of *Poria cocos* (Fuling) and *Alisma plantago-aquatica* (Zexie). It is traditionally categorized as a formula that promotes diuresis and leaches out dampness. In modern clinical research, particularly studies led by the Guangdong Provincial Hospital of Chinese Medicine, it is being evaluated for its ability to manage asymptomatic hyperuricemia. The decoction is hypothesized to lower serum uric acid levels by facilitating renal excretion and potentially modulating metabolic pathways, though its precise molecular mechanism involves multiple active botanical constituents acting on various renal transporters.

Other names
Fuling Zexie TangPoria and Alisma Decoction
02

Targets

URAT1 (Uric Acid Transporter 1)GLUT9 (Glucose transporter type 9)

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