Drug intelligence / Profile preview

furfuryl palmitate

Development stage
Unknown
Lead developer
Menarini
Modality
Small Molecules
Administration
Topical
01

Overview

Furfuryl palmitate is an ester formed from furfuryl alcohol and palmitic acid, used primarily as a topical antioxidant in dermatology. It acts by inhibiting the production of reactive singlet oxygen, thereby reducing oxidative stress in the skin. This mechanism helps to alleviate symptoms associated with atopic dermatitis (AD), contact dermatitis, eczema, xerosis, and other cutaneous inflammatory conditions. Furfuryl palmitate is incorporated into emollient creams and has been shown to reduce inflammation, itching, and improve skin barrier function. It is considered a steroid-sparing alternative for mild-to-moderate skin disorders due to its favorable safety profile and lack of significant side effects[1][2][4][6].

02

Targets

^1O2 (Singlet oxygen)

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