Drug intelligence / Profile preview

Futalin

Development stage
Preclinical
Modality
Small Molecules
Administration
Topical
01

Overview

Futalin is a topical non-steroidal anti-inflammatory drug (NSAID) formulated as an emulsion gel. Its active ingredient, diclofenac diethylamine, is designed to penetrate the skin to deliver localized pain relief and reduce inflammation. The drug exerts its therapeutic effects primarily by inhibiting cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which are crucial for the biosynthesis of prostaglandins—lipid compounds that mediate inflammation, pain, and fever. This mechanism leads to decreased prostaglandin production, thereby alleviating symptoms associated with various musculoskeletal conditions. It is used for conditions such as osteoarthrosis, external humeral epicondylitis, and other forms of joint and muscular pain.

Brand names
FutalinVoltaren EmulgelVoltaren
Other names
扶他林乳胶剂diclofenac diethylamine latex
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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