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Fuzheng Yangxin Decoction
- Development stage
- Unknown
- Administration
- Oral
01
Overview
Fuzheng Yangxin Decoction is a traditional Chinese medicine (TCM) herbal formula used primarily for the treatment of heart failure and related cardiovascular conditions. It consists of multiple herbs including Panax notoginseng, Panax ginseng, Rhodiola crenulata, Aconitum carmichaeli, Ophiopogon japonicus, Astragalus membranaceus, Angelica sinensis, and Rehmannia glutinosa[1][4]. The decoction is believed to work by supporting "Yangqi" in the heart according to TCM theory and has demonstrated clinical benefits in improving symptoms and surrogate endpoints in patients with chronic heart failure[1][2][4]. Its mechanism involves multi-target modulation affecting hundreds of biological targets identified through network pharmacology approaches; however, precise molecular mechanisms remain under investigation[1]. Clinical trials are ongoing to evaluate its efficacy and safety for heart failure with preserved ejection fraction (HFpEF)[4].
- Brand names
- Fuzheng Yangxin Decoction
- Other names
- FZYXFuzheng Yangxin RecipeFuzheng Yangxin Granule
02
Targets
STAT3 (Signal Transducer and Activator of Transcription 3)
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